ACETIC ACID OXIDATION BY ESCHERICHIA COLI: QUANTITATIVE SIGNIFICANCE OF THE TRICARBOXYLIC ACID CYCLE

Acetic acid oxidation by Escherichia coli; quantitative significance of the tricarboxylic acid cycle.

Krebs (1937) reported that acetate and a number of other substrates were oxidized under anaerobic conditions by nonproliferating suspensions of Eschrichia coli when fumarate was added as an oxidant. These observations resulted from a study of the role of fumarate in respiration, and no consideration was given to the mechanism of acetate oxidation. The over-all reaction for the oxidation of acet...

Acetic acid oxidation by Escherichia coli and Aerobacter aerogenes.

Evidence against the occurrence of the Krebs oxidation cycle in bacterial respiration has been steadily accumulating. Escherichia coli and many other bacteria do not readily metabolize the three tricarboxylic acids. Aerobacter aerogenes will not readily attack citrate when measured manometrically unless the organism is grown in the presence of this acid as the sole source of carbon. Recently Le...

The oxidation of tricarboxylic acid cycle compounds by Penicillium chrysogenum.

The presence of a tricarboxylic acid cycle in Penicillium chry8ogenum, as yet, has not been demonstrated conclusively. Ajl (1951) stated that of the mechanisms proposed for oxidation of the 2 carbon fragment in mold metabolism, the evidence for a tricarboxylic acid cycle is the least convincing. This paper presents a study of some of the enzymes of the tricarboxylic acid cycle in cell-free prep...

Quantitative aspects of the tricarboxylic acid cycle in baker's yeast.

The quantitative significance of the tricarboxylic acid cycle in the oxidation of acetate by yeast has remained in doubt despite many investigations concerning this topic. All of the enzymes of the tricarboxylic acid cycle have been demonstrated in either commercial baker's yeast or in pure cultures of Saccharomyces cerevisiae. (Weiland and Sonderhoff, 1932; Lynen and Neciullah, 1939; Novelli a...

Tricarboxylic Acid Cycle in